Muscle strength grade
Muscle function
M0
No active range of motion, no palpable muscle contraction
M1
No active range of motion, palpable muscle contraction only
M2
Reduced active range of motion – not against gravity, no muscle resistance
M3
Full active range of motion, no muscle resistance
M4
Full active range of motion, reduced muscle resistance
M5
Full active range of motion, normal muscle resistance
Table 18.2
International classification of surgery of the hand in tetraplegia – with additional resources for nerve transfers
Group | Spinal cord segment | Possible muscle transfers | Possible axon sources for nerve transfers |
---|---|---|---|
0 | ≥ C5 | No transferable muscle below elbow | Musculocutaneous nerve branches to coracobrachialis and brachialis muscle |
1 | C5 | Brachioradialis (BR) | Axillary nerve branches to deltoid and teres minor muscles |
2 | C6 | + Extensor carpi radialis longus (ECRL) | Radial nerve branches to supinator or ECRB muscles |
3 | C6 | + Extensor carpi radialis brevis (ECRB) | |
4 | C6 | + Pronator teres (PT) | |
5 | C7 | + Flexor carpi radialis (FCR) | |
6 | C7 | + Extensor digitorum | |
7 | C7 | + Extensor pollicis longus | |
8 | C8 | + Flexor digitorum | |
9 | C8 | No intrinsic hand muscles | |
10 (X) | Exceptions |
Joint range of motion: Passive joint motion, above all in the shoulder, elbow, forearm, wrist, MCP, and PIP joints, is prerequisite for reconstruction. Tenodesis effect during wrist extension (hand closure) and flexion (hand opening) and joint stability (primarily thumb CMC joint) is preferable but not required for reconstruction.
Sensibility testing: Sensory examination focuses on cutaneous afferences with a 2-point discrimination of 10 mm or better in the thumb for cutaneous control (Cu); otherwise ocular control (O) is required [10].
Therapeutic Options
Nonoperative Treatment
Dedicated physiotherapy and occupational therapy including splinting optimize preoperative circumstances and postoperative function. It provides the “other half” of rehabilitation by patient motivation, retraining of transferred tendons, edema control, and contracture prevention and is, besides input from rehab specialists and the patients themselves, essential for successful rehabilitation [3, 13, 14].
Surgical Treatment
Indications for Surgery
Specific requirements must be met preoperatively (Table 18.3).
Table 18.3
Preoperative requirements in tetraplegia surgery
1 | Neurological functional plateau – no further recovery expected |
2 | Emotional stability – accepting the consequences of injuries |
3 | Realistic expectations and postoperative goals |
4 | No open wounds or pressure sores (decubitus), no infections (e.g., bladder) |
5 | Motivation and ability of the patient to cooperate actively in aftertreatment |
6 | Treatment plan based on clinical examination and counseling of the patient |
7 | Available donor muscles (muscle strength grade ≥M4) |
8 |
Time Management
The abovementioned conditions are usually achieved after completing the first rehabilitation, yet strict time rules (e.g., no operations before 1 year since injury) are not appropriate. Neurological stability may be achieved after 3–6 months in complete tetraplegia. Early surgery has many advantages, such as faster reintegration. Often, however, financial, family, or work-related problems must be solved first. Notably, a tendon transfer reconstruction remains feasible even decades after SCI. In incomplete SCI, functional recovery takes longer so that treatment plans should be developed only after complete regeneration spasticity control [12].
Regarding nerve transfers, muscles in SCI can be categorized into:
- 1.
Still functional muscles innervated by the supralesional segment
- 2.
Muscles with damaged anterior horn cells and lower motor neuron denervation
- 3.
Paralyzed muscles innervated by infralesional segment
The first group represents potential donor nerves; the nerves to the latter two groups are potential recipients. Early surgery (within 1 year) is critical, as neuromuscular end-plate degeneration makes the denervated muscle refractory to eventual reanimation (after about 2 years). In upper motoneuron lesions, neuromuscular degeneration is slowed which may extend the time window for successful nerve transfers [15, 16].
Goals of Surgery
Surgical operations aim at better daily life performance (Table 18.4).
Table 18.4
Surgical procedures (excluding nerve transfers) to achieve patients’ ability goals
Ability goal | Functional goal | Procedure |
---|---|---|
Stabilizing elbow in space, reaching overhead objects, propelling wheelchair, stabilizing trunk | Elbow extension | Reconstruction of triceps function Posterior deltoid-triceps Biceps-triceps |
Use of utensils, hand writing, propelling wheelchair | Hand closure | Reconstruction of grip |
Reconstruction of passive key pinch BR-ECRB FPL-radius CMC 1 arthrodesis Reconstruction of active key grip BR-FPL CMC I arthrodesis Split FPL-EPL tenodesis Reconstruction of finger flexion ECRL-to-FDP 2–4 | ||
Reaching for objects, e. g., glass, thumb and finger positioning for improved grasp control | Hand opening | Reconstruction of thumb and finger extensors |
Passive opening CMC I arthrodesis EPL to extensor retinaculum attachment | ||
Active opening PT-EDC and EPL/APL | ||
Thumb stabilization ELK procedure, CMC 1 arthrodesis | ||
Reconstruction of intrinsics Zancolli-Lasso tenodesis House tenodesis EDM-APB |
Reconstructive algorithms depend on the level of paralysis (Table 18.5).
Table 18.5
Surgical algorithms according to International Classification (IC)
IC group | Recommended surgical procedure |
---|---|
0 | Abducted shoulder (anterior deltoid muscle transfer) Flexion contracture of the elbow (biceps tendon Z-tenotomy) Supinated but not contracted forearm (Zancolli biceps rerouting – check presence of supinator muscle!) Fixed supination contracture – osteotomy of radius |
1 | BR-to-ECRB for active wrist extension Moberg’s key pinch procedure ELK procedure |
2 | BR-to-FPL (active key pinch) CMC 1 fusion ELK procedure EPL tenodesis to dorsal forearm fascia |
3 | BR-to-FPL ECRL-to-FDP 2–4 ELK procedure House intrinsic procedure CMC 1 fusion EPL tenodesis |
4 | BR-to-FPL ECRL-to-FDP 2–4 ELK procedure House intrinsic procedure CMC 1 fusion EPL tenodesis |
5 | BR-to-FPL ECRL-to-FDP 2–4 ELK procedure House intrinsic procedure CMC 1 fusion EPL tenodesis |
6 | BR-to-FPL ECRL-to-FDP 2–4 ELK procedure House intrinsic procedure EDM-to-APB transfer EDC-to-EPL |
7 | BR-to-FPL ECRL-to-FDP II-IV ELK procedure (if required) House intrinsic procedure EDM-to-APB or EIP-to-APB |
8 | BR-to-FPL ECRB-activated ADPB Opponens plasty (EIP, EDM, FCU) Active Zancolli lasso procedure (ECU) House intrinsic procedure |
9 | House intrinsic procedure |
10 | Pathological postures (MP joints fixed in hyperextension, lack of any functioning intrinsic muscles, wrist fixed either in flexion or extension, etc.) Release of contracted muscles, joint capsules, tendon lengthenings |
Surgical Techniques
Reconstruction of Elbow Extension
Elbow extension is critical for overhead activities, weight shifting, and transfers and greatly increases wheelchair propulsion and workspace of the hand by 800 %. Elbow restoration should precede grip reconstructions because:
Use of a hand that cannot reach out is limited.
Elbow extension stabilizes the trunk in the wheel chair.
Stability enables more controlled hand use.
Tendon transfer functions (e.g., using brachioradialis) improve with antagonistic elbow extension.
Procedures to restore triceps function include:
Posterior deltoid transfer reliably restores triceps function in C5/C6 tetraplegia (Fig. 18.1a, b). Candidates for biceps transfer usually demonstrate intact and functional brachialis and supinator muscles and elbow flexion contracture exceeding approximately 20°. Both techniques are time proven and provide improved arm control useful in many daily activities. Alternatively, triceps reanimation is possible by transferring fascicles of axillary (branches to posterior portion of deltoid or teres minor muscle) or musculocutaneous (brachialis branch) nerve [15, 16].
Fig. 18.1
(a) C5–C6 tetraplegic patient demonstrates his restored elbow extension after posterior deltoid-to-triceps reconstructions. (b) After reconstruction of elbow extension by posterior deltoid-to-triceps muscle transfer, the operated arm is immobilized in an arm rest between training sessions in elbow extension and 30° of shoulder abduction to protect the tendon attachment, e.g., from excessive shoulder adduction. Elbow flexion is then increased by 10–15° per week using an adjustable orthosis until full flexion is allowed
Reconstruction of Forearm Pronation
Supination contracture due to imbalance between the functional biceps brachii and supinators and weak or paralyzed pronators seriously impairs hand function and increases the risk of gravity-induced wrist extension contracture. Restoration of forearm pronation re-enabling key pinch is possible by:
Reconstruction of Wrist Extension
- 1.
BR-to-ECRB tendon transfer
Reconstruction of active wrist extension is highly important to enable wrist-related tenodesis effect. If wrist extension is absent (IC group 0 and 1), the brachioradialis (only IC group 1) can be transferred onto the ECRB for wrist extension-driven key pinch after additional FPL-to-radius tenodesis (Moberg procedure) [7].
- 2.
Nerve transposition from above the elbow
If antigravity wrist extension is absent and cannot be restored by tendon transfer because donors lack below elbow (group 0) in C5 tetraplegia, tenodesis grip can be restored by brachialis motor nerve transfer to the ECRL motor branch and FPL-to-radius tenodesis [19].
Positioning and Stabilization of the Thumb
Interphalangeal (IP) joint hyperflexion disturbs thumb function if extrinsic flexor function is preserved or reconstructed (e.g., by FPL reanimation) but intrinsic or extrinsic thumb extensors are paralyzed. The EPL-loop-knot (ELK) procedure has advantages compared to FPL split tenodesis or arthrodesis (Fig. 18.2) [20].
Fig. 18.2
EPL-loop-knot (ELK) procedure to stabilize the thumb interphalangeal joint and prevent it from hyperextension: The EPL tendon is mobilized and elevated with a hook and then duplicated by forming a loop of the tendon and suturing this loop onto the tendon itself proximally