Prospective Multicenter, Multinational Study to Evaluate the Safety and Efficacy of Concurrent Collagenase Clostridium Histolyticum Injections to Treat Two Dupuytren Contractures in the Same Hand



Fig. 18.1
Mean flexion contractures from baseline to day 31



A352582_1_En_18_Fig2_HTML.jpg


Fig. 18.2
Range of motion at baseline and day 31



Table 18.1
Most common treatment-related AEs











































AE, n (%) (n = 715)

Different fingers

Different fingers

Fingers

Same finger

Both MP Total (n = 244)

Both PIP (n = 72)

1 MP/1 PIP (n = 58)

1 MP/1 PIP (n = 351)

At least 1 AE 680 (95.1)

228 (93.4)

71 (98.6)

55 (94.8)

336 (95.7)

Edema peripheral 552 (77.2)

186 (76.2)

56 (77.8)

47 (81.0)

271 (77.2)

Contusion 419 (58.6)

145 (59.4)

49 (68.1)

36 (62.1)

197 (56.1)

Pain in extremity 361 (50.5)

116 (47.5)

41 (56.9)

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Oct 4, 2017 | Posted by in ORTHOPEDIC | Comments Off on Prospective Multicenter, Multinational Study to Evaluate the Safety and Efficacy of Concurrent Collagenase Clostridium Histolyticum Injections to Treat Two Dupuytren Contractures in the Same Hand

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