of Rotator Cuff Tear



Fig. 1
The figure shows the hematoxylin and eosin staining of the rotator cuff tear (Å~5). Chronic inflammatory infiltrate, fibroblasts proliferation, and sclerosis, that are related to neoangiogenesis, are observable



A369816_1_En_5_Fig2_HTML.gif


Fig. 2
The figure shows a characteristic neoangiogenesis and fibroblast proliferation with collagen fibers displayed in random arrangement (E/E 20×)


A369816_1_En_5_Fig3_HTML.gif


Fig. 3
(a) Tendon: capillary proliferation and increased cellularity (H/E 109). (b) Tendon: chondral metaplasia: chondrocytes-like cells were either clustered in groups or randomly dispersed in the matrix (H/E 40×). (c) Tendon: collagen fibers appear discontinuous and disorganized (Masson’s trichrome 209). (d) Tendon: chondral metaplasia: alcian blue staining provides the histochemical demonstration of the presence of sulfated glucosaminoglycans (40×). (e) Bursa: bursal samples showed edema, capillary proliferation, and hypertrophy/hyperplasia of synoviocytes (H/E 10×). (f) Bursa: fibrosis, necrosis, and calcifications (H/E 20×)


A369816_1_En_5_Fig4_HTML.gif


Fig. 4
The figure shows the positive cells (brown) after immunohistochemical stain for anti-p65 antibody on the margins of the rotator cuff tear


Summarizing, histopathological findings suggest that changes in collagen and proteoglycans types and amount, degenerative modifications, and chondrometaplasia lead tendons to weakness and predispose it to the tear; the bursal tissue may play a prominent role in the healing process; stem cell role has to be deeply investigated.

Jul 14, 2017 | Posted by in ORTHOPEDIC | Comments Off on of Rotator Cuff Tear

Full access? Get Clinical Tree

Get Clinical Tree app for offline access