Fig. 10.1
Photograph depicting an implant specific tibial sleeve (DePuy; Warsaw, IN)
Recent Innovations
In 1999, Bobyn et al. [12] studied cylindrical porous tantalum implants in a transcortical canine model . Two pore sizes (430 and 650 μm) were used, and the shear strength of the bone-implant interface was assessed. At 4 weeks postoperatively, the authors found the extent of filling of both the smaller and larger pores with new bone ranged from 40 to 50%, and by 16 and 52 weeks, the filling grew to 63–80%. In addition, mechanical tests indicated a shear fixation strength of at least 18.5 MPa, which is substantially higher than other less porous materials [24–26]. The primary benefit of this material is that the modulus of elasticity approximates that of the bone, thereby promoting osseointegration and avoiding periprosthetic stress shielding . The results of this study were promising, prompting the 2008 landmark study assessing the use of porous tantalum in humans.
Meneghini et al. [27] studied porous tantalum metaphyseal cones (Trabecular Metal [TM]; Zimmer; Warsaw, Indiana) in 15 patients (eight females, seven males; mean age 68 years) undergoing revision TKA (Fig. 10.2). The patients had an average of 3.5 prior total knee replacement procedures, and classification of tibial bone loss , assessed intraoperatively, included Type 2B [7] and Type 3 [8]. At the final follow-up (mean 34 months), all 15 cones showed evidence of osseointegration, and there was no evidence of loosening or migration of any of the tibial reconstructions. Four patients required reoperation for the following reasons: recurrent deep infection [2], pain secondary to aseptic loosening of the femoral component [1], and acute periprosthetic tibial fracture sustained during a fall [1]. The overall average Knee Society clinical scores [28] improved by 33 points.
Fig. 10.2
Intraoperative photograph of a revision total knee arthroplasty and an Anderson Orthopaedic Research Institute (AORI) Type 2B defect treated with a tantalum femoral cone (Zimmer; Warsaw, IN)
Based on the initial success of porous tantalum metaphyseal cones and acetabular components [29–34], there has been an explosion of investigation and development of alternative porous metal constructs, primarily using titanium rather than tantalum [35–38]. These approaches have included a variety of technologies to produce a porous metal construct. However, the most promising and cost-effective approach seems to be that of three-dimensional (3-D) printing of implants [39–41].
3-D Printed Titanium Cones
This newly released cone system is based on an intramedullary guided milling system that provides very precise bone preparation which increases implant stability and apposition of the cone to available host bone. These cones are unlinked to a specific prosthesis and, like the tantalum cones, are inserted independent of the prosthesis being used. The tibial shapes and sizes are designed so that the simple symmetric shapes can be used in cases that one would typically use sleeves rather than cones (i.e., Type 1 and 2A bone defects). The lobe-shaped cones are designed to be used in Type 2B and Type 3 bone defects (Fig. 10.3). These cones require less bone removal, and bone preparation time is significantly less than freehand high-speed burrs.
Fig. 10.3
The innovative 3-D printed titanium tibial cones come in asymmetric shapes with lobes to allow for bottoming out at the junction of the metaphysis and diaphysis (Stryker; Mahwah, NJ)
The femoral cones are based on a bilobed design that allows the lobes to bottom out at the junction of the metaphysis and diaphysis so that the diaphyseal portion of the cone cannot be inserted beyond the preparation area (Fig. 10.4). This design feature was incorporated to avoid longitudinal fractures of the distal femur that have been observed with the tantalum cone designs.
Fig. 10.4
The innovative 3-D printed titanium femoral cones come in bilobed shapes to allow for bottoming out at the junction of the metaphysis and diaphysis (Stryker; Mahwah, NJ)
Surgical Technique
Metaphyseal Sleeves
Once the surgeon has classified the bone defect, a starter reamer is used to open the metaphyseal bone until the desired symmetry is achieved for subsequent sleeve placement [42]. Trial sizing of components is performed, and once the appropriate size is selected, the sleeve is placed. Usually a tapered junction that is system specific is used to connect the sleeve to the stem, rather than cement [8]. Both cemented and cementless stems are available for use. When using a cemented stem proximal to the femoral sleeve or distal to the tibial sleeve, the combination sleeve and stem is cemented by filling the femoral and tibial canals with cement prior to insertion of the components. In a cementless system, the stems are impacted into the metaphyseal-diaphyseal bone of the distal femur and/or proximal tibia in order to achieve adequate axial and rotational press fit. Bone graft is used to fill any voids that exist between the host bone and the sleeve.
The advantages of this approach include a straightforward surgical technique that can be effectively used in mild to moderate bone loss. The disadvantages of this approach are that the preparation broaches can be difficult to use in sclerotic bone, and these sleeves are intrinsically specific to one implant system.
Porous Tantalum Cones
The surgical technique for porous tantalum metaphyseal cones has previously been described [8, 27, 43, 44]. Once the surgeon has decided to use a metaphyseal cone, a trial intramedullary stem or reamer may be used to create the appropriate positioning of the cone. Trial sizing of the cone is done by inverting the cone to match the size most closely to the proximal part of the defect in the tibia or the distal part of the defect in the femur. Due to the variability of bone defects, cones can be contoured, usually to accommodate large defects. The bone is then contoured free hand with a high-speed burr to ensure optimal press fit. The cone is impacted into its final position, and trial components and stems are inserted. The final sized implant and stem are inserted through the cone into the correct rotational alignment. The interface between the cone and stemmed implant is reinforced with cement. It is our preference to only utilize cemented stems. When using a cemented stem proximal to the femoral cone or distal to the tibial cone, the stem is passed through the cone, placed in the cement, and held in place until the cement hardens. Bone graft is used to fill any voids that exist between the host bone and the cone.
The advantages of these metaphyseal cones are that there are multiple shapes and sizes to accommodate a large spectrum of bone defects in the moderate to severe range of bone loss. Additionally, the porous tantalum can be cut with a high-speed burr to alter the shape and size if needed. The primary disadvantage of these cones is that the bone preparation is done with high-speed burrs in a freehand manner, which results in a less than optimal bone preparation in many cases and is often quite time-consuming. Additionally, the size and shape of these implants often require considerable bone removal, and this is particularly true of the femoral cones.
3-D Porous Titanium Cones
Once the surgeon has decided to use a metaphyseal cone, the canal is reamed up to a diameter so that the reamer is stable within the canal. Based upon the intended size of the prosthesis, a target range of cone sizes can be anticipated to gauge the depth of the central symmetric cone reamer (Fig. 10.5). In the tibia, a determination can then be made as to whether or not it is desirable to proceed with additional bone preparation for the lobed-shaped cone. If so, a side reamer is used in the appropriate position to prepare the lobe portion of the bone preparation (Fig. 10.6). Symmetric and lobe-shaped trials are then used to judge final position of the cone in relation to the prosthesis. In the femur, the cones are bilobed. The femoral bone preparation is also medullary guided, initiated with a central reamer, and then finally with two-side lobe reamers (Fig. 10.7).
Fig. 10.5
For the 3-D printed titanium cones, a central symmetric cone reamer is used to gauge the depth of the cone, and a trial from a variety of sizes and shapes can be selected (Stryker; Mahwah, NJ)
Fig. 10.6
If a lobed-shaped cone is selected, a side reamer is utilized in the appropriate position to prepare the lobe portion of the bone (Stryker; Mahwah, NJ)
Fig. 10.7
As with the tibia , the femoral cone has a central reamer and lobes that are milled and is inserted with the intention of bottoming out and preserving the bone (Stryker; Mahwah, NJ)
It is important to note that both the tibial and femoral cones are inserted with a stem trial to guide appropriate implant position. The final sized implant and stem are inserted through the cone into the correct rotational alignment. The interface between the cone and stemmed implant is reinforced with cement. It is our preference to only utilize cemented stems. When using a cemented stem proximal to the femoral cone or distal to the tibial cone, the stem is passed through the cone, placed in the cement, and held in place until the cement hardens. Bone graft is generally not required to fill any voids that exist between the host bone and the cone because of the precise nature of the bone milling preparation (Figs. 10.8a, b).
Fig. 10.8
Anteroposterior (a) and lateral (b) radiographs of a reimplanted total knee arthroplasty with 3-D printed titanium femoral and tibial cones
The advantages of these 3-D printed porous titanium cones include more precise and rapid bone preparation, less bone removal, and better axial alignment due to the use of a medullary guided bone preparation system. The disadvantages of this system are yet unknown as there have been no clinical studies yet reported.
Key Technical Points
When bone defects are encountered in revision TKAs, there are five general steps that are critical:
- 1.
Classify intraoperative bone defect using the AORI classification system.
- 2.
Contour the metaphysis to get an optimal fit with a sleeve or cone.
- 3.
Impact the sleeve or cone.
- 4.
Fill defects between the sleeve or cone and host bone with bone graft to promote bone ingrowth.
- 5.
Bypass prosthesis and cone with mid-length cemented stem to provide rigid initial fixation until cone has time to ingrow.
Clinical Outcomes
Metaphyseal sleeves and cones, in comparison to their alternative allografts, have several advantages: implementation through a simpler technique, shorter operative times, decreased risk of transmitting infection, and potentially more durable fixation [45–48]. Recent literature has further stressed these advantages.
Metaphyseal Sleeves
Metaphyseal sleeves have been available for revision TKAs for almost four decades, yet most data is relatively short term (Table 10.1). In 2014 , Barnett et al. [48] retrospectively reviewed 34 revision TKAs using stepped porous titanium metaphyseal sleeves (DePuy) in 34 patients (13 females, 21 males; mean age 66 years). The patients had a mean of 0.22 (range, 0–2) prior knee revisions after the primary TKA, and classification of bone loss, performed intraoperatively, included Type 2A [14], Type 2B [15], and Type 3 [5]. At the final follow-up (mean 38 months), all 34 sleeves showed radiographic evidence of osseointegration, and there were no signs of implant migration or fracture. Three patients required reoperation for the following reasons: failure of femoral adaptor [1], supracondylar femoral fracture [1], and intractable end-of-stem pain [1]. The Knee Society functional scores improved by a mean of 34 points, and knee scores improved by a mean of 47 points.
Table 10.1
Comparison of results with metaphyseal sleeves for revision TKAs in the literature
Barnett et al. [48] | Huang et al. [42] | Bugler et al. [49] | |
---|---|---|---|
Year | 2014 | 2014 | 2015 |
Mean age | 66 | 64 | 72 |
No. of patients | 34 | 79 | 35 |
No. of revision TKAs | 34 | 83 | 35 |
AORI types included | 2, 3 | 1, 2, 3 | 1, 2, 3 |
No. of tibial sleeves | 34 | 83 | 10 |
No. of femoral sleeves | 0 | 36 | 1 |
No. of both tibial and femoral sleeves | 0 | 0 | 24 |
Mean follow-up (months) | 38 | 29 | 39 |
Osseointegration rate (%) | 100 | 100 | 100 |
Reoperation for any reason (%)a | 8.8 | 16.9 | 0 |