Mesenchymal Chondrosarcoma




Location: Trunk and craniofacial bones. Rare in the limbs.

Clinical: Pain and swelling.

Imaging: On x-ray – osteolytic lesion with permeative destruction of bone, ill-defined margins, breaking the cortex, with soft tissue mass, and with faded typical calcifications.

Histopathology: Dense round cells proliferation with hemangiopericytoma-like architecture. Within the tissue there are small foci or larger islands of well-differentiated hyaline cartilage.

Course and Staging: Fast growth, high rate of recurrence with inadequate surgery, and frequent metastases. Usually, IIB.

Treatment: Wide or radical resection. Chemotherapy is used but its real effectiveness is not yet known. Prognosis is poor.


Key Points




















Clinical

Very rare in bone, adults, pain, and swelling

Radiological

Aggressive osteolysis, with possible calcification

Histological

Mixed population with isles of cartilagine and undifferentiated round cells

Differential diagnosis

None

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Feb 19, 2017 | Posted by in MUSCULOSKELETAL MEDICINE | Comments Off on Mesenchymal Chondrosarcoma

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