Exercise-Induced Bronchoconstriction Testing



Exercise-Induced Bronchoconstriction Testing


Meghan F. Raleigh

Fred H. Brennan Jr



EPIDEMIOLOGY



  • Exercise-induced bronchoconstriction (EIB) is a common medical condition that affects at least 10%-15% of athletes (9).


  • Exercise-induced asthma (EIA) is the presence of similar symptoms in a patient with a known diagnosis of asthma (18). The prevalence of EIB in asthmatic patients is 80%-90% (19).


  • Respiratory symptoms alone are insensitive in predicting bronchospasm in athletes (11).


  • Common respiratory symptoms suggestive of asthma (coughing, wheezing, etc.) have only a 60%-70% positive predictive value for EIB (15,16).


INDICATIONS FOR EIB TESTING



  • An athlete with signs or symptoms suggestive of EIA.


  • An athlete with known chronic asthma may be tested for an exercise-triggering event.


  • An athlete with exertional dyspnea, once cardiac etiologies have been clinically and/or diagnostically eliminated.


CONTRAINDICATIONS FOR EIB TESTING



  • Active or recent pulmonary infection within past 30 days.


  • Ongoing or recent exacerbation of asthma.


  • Known allergy to methacholine (methacholine challenge).


  • An athlete using inhaled corticosteroids may still be tested; however, the provocation test may be falsely negative in up to 50% of patients (2,17).


EIB PROVOCATIVE TESTING


Exercise Challenge



  • A baseline pulmonary function test (PFT) should be performed and results recorded prior to this provocative test.


  • The sensitivity and specificity of this test for identifying EIB in athletes are approximately 65% (6,9).


  • The challenge should be sport-specific and conducted in the environment in which athletes most commonly experience their symptoms (7).


  • An exercise challenge may be used as a first-line diagnostic study.


Conducting an Exercise Challenge



  • Allow athletes to stretch, but do not allow them to exercise or warm up prior to the challenge. A warm-up period may result in a false-negative result.


  • Obtain a baseline PFT or peak expiratory flow rate (PEFR). Record FEV1 (forced expiratory volume in 1 second) and FEF\25-75 (force expiratory flow during the middle portion of expiration), or PEFR.


  • The sport-specific exercise should be conducted for 8-10 minutes at 85%-90% of maximum calculated heart rate (220 − age in years = calculated maximum heart rate).


  • After 10 minutes of exercise, allow a 1-minute rest. Check PFT or PEFR three times and record the best result.


  • Repeat these measurements at 3, 5, 10, 15, and 20 minutes after termination of the exercise challenge.


  • A decrease of > 10% in the FEV1 or PEFR and/or a decrease in FEF25-75 of > 20% are diagnostic for EIB (10,13,14).

May 22, 2016 | Posted by in SPORT MEDICINE | Comments Off on Exercise-Induced Bronchoconstriction Testing

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