Anterior Tether for Growth Modulation
Peter O. Newton
INDICATIONS/CONTRAINDICATIONS
Anterior spinal tethering is a technique designed to alter the growth of an immature patient with thoracic scoliosis. The basic premise is that vertebral growth and alignment can be mechanically altered in a positive way by applying a flexible tether along the lateral aspect of the vertebral bodies. Much the way stapling and plating asymmetrically across the physis of long bones in children has been used to correct limb alignment, so have tethering procedures been applied in the setting of scoliosis. Altered growth of the scoliotic spine results in a three-dimensional deformity of the spine associated with a coronal plane curvature, axial plane rotation, and frequently a loss of thoracic kyphosis. Tethering the anterior column via the chest on the convex side of the curve is performed in hopes of directly addressing the coronal and sagittal deformities and ultimately leading to couple rotational correction.
The indications for such a procedure have not been clearly established, and there are various opinions on which curves in which patients made ideal candidates for this relatively new approach to managing scoliosis. If the goal is growth modulation, then clearly “significant” growth should be remaining. It is my intention to grow the spine into an improved alignment as I have little faith that long-term correction can be achieved with an unfused instrumentation procedure. As the indications for this approach are defined, I prefer to limit such a growth-modulating approach to patients who are Risser stage 0 with greater than 2 years of growth remaining. On the other hand, juveniles may have relatively small vertebrae in the thoracic region compared with available tethering implants. A lower age limit of approximately 9 years is suggested.
Curve size is also critical—too large a curve and the instrumentation may not be able to alter the mechanics of growth sufficiently to create improvement; too small a curve may result in rapid overcorrection or unnecessary surgery. Only patients with curves that would otherwise require spinal fusion procedures are those considered for surgical tethering. This sets the lower limit at approximately 45 degrees for those patients progressing despite bracing. The upper limit is poorly defined at present but likely is in the 60- to 70-degree range.
The tether seems most appropriate for single major thoracic curves, although the magnitude of compensatory curves that will respond spontaneously as the thoracic curve improves is unclear both for the upper thoracic and lumbar regions. Curves in the upper thoracic and lumbar spine should not be so large as to be indicated for spinal fusion on their own. The formation and segmentation of the vertebrae should be normal.
EDITOR’S NOTE
If preoperatively the left shoulder, clavicle, or ribs are high on the left side, this is likely to worsen as the main curve corrects over time from an anterior tether. Scoliosis that would be treated posteriorly with instrumentation above T4 to keep the left shoulder low may be considered by some to be a relative contraindication for anterior tether surgery, which may cause a progressively higher left shoulder over time. This possibility should be shared with the family preoperatively.
Summary of Indications
Age ≥ 9 years old
≥2 years of remaining growth
Thoracic major scoliosis without congenital malformations
Cobb 45 to 65 degrees
Nonstructural compensatory curves
Instrumented levels between T5 and L1
In addition to patients who do not meet the above indications, patients who would not tolerate an open or endoscopic approach through the chest should also be managed by other methods. Curves that extend into the lumbar region are difficult to span with a tether, and there is some concern that anterior tethering in the lumbar spine may induce some undesirable loss of lumbar lordosis.
PREOPERATIVE PREPARATION
There are no currently available implants approved by the US FDA for this procedure, as such the surgeon may wish to inform the patient and parents of this fact. The implants currently available in the United States and abroad have been approved for posterior lumbar-instrumented fusion.
Preoperative planning is required to assess the vertebral body width and height to ensure implants of appropriate size can be obtained or if needed trimming the screws to length can be anticipated. A high-speed diamond-cutting wheel or rod cutter may be used to cut the screws to length. The tips should be smoothed to remove any sharp edges as the screws are placed with bicortical fixation in a position that may be in close proximity to the aorta and lung tissue.
The levels instrumented are those of the measured Cobb angle, understanding, however, that the disc and vertebral wedging the tether is designed to correct are maximal at the apex. This suggests a need for differential tethering, which may be accomplished by applying more versus less tension in the device. Some sense of the curve flexibility can be gained from side-bending radiographs. This can be enticing as most of these young patients have very flexible curves. However, correction should be limited based on the number of years of remaining growth. Too much initial correction is likely to lead to early overcorrection and a requirement for tether loosening or removal. Exact prediction for the ideal residual deformity based on remaining growth and curve pattern do not yet exist.
SURGICAL PROCEDURE
The intrathoracic exposure is greatly facilitated by single-lung ventilation. This is helpful in open and miniopen approaches and essential in thoracoscopic approaches. In general, a double-lumen endotracheal tube placed under flexible bronchoscopic control is preferred; however, in some smaller patients, a bronchial blocker may be the only option.
Patient positioning is in the direct lateral decubitus position, taping and bolstering the patient securely. Recheck the position of the double-lumen tube as it may shift with turning. The arms are positioned in 90 degrees of both shoulder and elbow flexion, giving access to the axilla.
Planning for portal placement if a thoracoscopic approach is to be utilized can be done with the image intensifier in the cross-table anterior-posterior position. The coronal angulation of each of the levels to be instrumented can be identified with a rod placed on the back so a line can be drawn on the skin (Fig. 50-1). Plan for two to three screws per portal site, generally three along the posterior axillary line (Fig. 50-2). An additional anterior portal is preferred for the thoracoscope. These same skin markings are similarly useful if a miniopen approach is planned.