Telehealth succeeds when virtual visits feel simple for patients and manageable for staff. The API layer often decides that experience, from scheduling and reminders to how fast a call connects and how securely data moves. 

This article compares seven telehealth API tools with different strengths, including HIPAA-aligned video and voice, conferencing at scale, streaming, and open-source options. It also covers practical features that affect day-to-day operations, such as waiting rooms, captions, recordings, analytics, and regional data controls. 

Use these examples to match technical capabilities to your care model, whether you run high-volume visits, follow-up heavy specialties, or education programs.

iotum

Telehealth tools only help if they reduce friction for patients and staff. The best options support scheduling, smooth join flows, and secure virtual visits, while keeping records easy to review later. This section looks at iotum as part of a “best telehealth API tools” shortlist, focusing on what it supports across appointment management, remote consultations, and post-visit analytics.

It is built around a HIPAA-compliant video and voice conferencing API, with features like click-to-join invitations, waiting rooms, and recorded-session insights that can feed back into care and operations.

iotum Key Features

• Appointment management: Scheduling API with SMS and email notifications, plus automatic and customizable invitations and reminders, and click-to-join access.
• Remote consultation tools: Download-free video and voice, dial-out to patients, works on any device with an internet connection, text chat, document and screen sharing, waiting room, live video annotation, recording, and closed captions.
• Integrations and workflow fit: Listed integrations include Google Calendar, YouTube streaming, and Outlook.
• Security controls: Mentions data sovereignty across regions, WebRTC standards, AWS and DigitalOcean hosting, plus Meeting Lock, one-time access codes, and secure rooms

iotum Pros

• Fewer missed connections: Reminders, invitations, and click-to-join flows are positioned to reduce join issues and appointment delays.
• Stronger visit documentation: Recording, transcriptions, and searchable playback support follow-ups, reviews, and continuity across care teams.
• Actionable session analytics: Highlights include speaking time per party, sentiment analysis with positive and negative highlights, and extracted keywords, dates, names, and places.
• Practical access features: Waiting rooms, captions, and collaboration tools help virtual visits work for different patient needs and visit types

iotum Best Use Case

• Practices running high volumes of virtual appointments that need scheduling, reminders, and quick join links baked into the flow.
• Clinics and hospitals coordinating across locations where consistent documentation, controlled access, and centralized visit records matter.
• Specialist care and follow-ups where recording, transcripts, and searchable visit history support continuity.
• Medical education and procedure review that benefits from real-time interactive video, annotation, and multi-camera support as described on iotum.com.

100ms.live

100ms.live takes a unique approach to video infrastructure worth learning about.

100ms.live Key Features

100ms.live combines video conferencing with live streaming in a single SDK:

• Live video calls support up to 10,000 participants with sub-second latency
• Millions of viewers can access streaming instantly
• HIPAA compliance ensures data encryption both in transit and at rest
• Streams feature custom layouts and persistent participant states
• Virtual backgrounds and noise reduction come with video and audio plugins
• Users can choose regional data storage options (USA, Europe, India)
• SIP calling integration enables audio dial-in/dial-out

100ms.live Pros

100ms.live handles challenging scenarios that typically crash video calls. VPN connections, device capturing, network switching, and interruptions work smoothly.

Their pricing structure includes 10,000 free minutes monthly for both conferencing and streaming. Small-scale implementation and testing become economical.

The platform’s exceptional stability comes from its creators – the team behind infrastructure for some of the world’s largest live events.

100ms.live Best Use Case

100ms.live excels in telehealth apps that need both private consultations and large-scale health education. To cite an instance, see how FixHealth merged its ML models with 100ms.live in just one week. This created a system providing live posture feedback during physical therapy sessions.

Galene

Galene distinguishes itself as an open-source videoconference server among HIPAA-compliant telehealth platforms.

Galene Key Features

This lightweight platform delivers these telehealth capabilities:

• Handles multiple audio/video streams while supporting text chat
• Saves sessions directly to disk for patient documentation
• Displays user status indicators including “raise hand” function
• Provides various codec options (VP8, VP9, H.264, AV1)
• Creates low-latency connections with built-in TURN server
• Controls network congestion through bandwidth estimation
• Offers HTTP-based API for creating groups and users

Galene Pros

Galene evolved from an educational platform into a solution that serves healthcare communication needs. Major universities and international conferences now rely on its capabilities. The platform’s lightweight design makes it ideal for facilities with limited technical resources.

Galene Best Use Case

Patient education sessions excel on Galene, which hosts about 300 participants per server core. The platform handles telehealth consultations smoothly with 20 participants on one core and scales up to 40 participants with four cores. 

Videos may briefly freeze under heavy load but recover quickly when camera usage drops. The platform’s performance in areas with poor internet connectivity makes it valuable for rural telehealth programs.

Brightcove

Brightcove provides an enterprise-grade video platform that works well as a HIPAA compliant telehealth solution.

Brightcove Key Features

Brightcove’s cloud-based video platform delivers these essential healthcare capabilities:

• Adaptive bitrate streaming that adjusts video quality based on network conditions
• Live streaming with DVR functions for medical conferences and training
• Advanced analytics that track viewer patterns and engagement
• Video playback support on desktop and mobile devices
• Content protection features like token authentication and IP restrictions
• REST APIs that give access to almost every platform function
• Native app integration with iOS, Android, iPadOS, and tvOS

Brightcove Pros

Brightcove makes video workflows efficient through its complete APIs and detailed documentation in six languages. Medical institutions value their reliable streaming capabilities for healthcare communication. 

The platform’s security features are particularly strong – domain controls restrict viewing to authorized websites while TLS encryption protects data transfer. RESTful APIs enable smooth integration with existing video management systems and content platforms through CMS connectors.

Brightcove Best Use Case

Brightcove excels in several healthcare scenarios. Medical education programs benefit from its high-quality streaming capabilities. Patient education libraries work well with its content protection features. Healthcare marketing campaigns can learn about audience behavior through detailed analytics. The platform serves healthcare organizations that need reliable video delivery without complex customization.

JW Player

JW Player provides professional video streaming through cloud technology. It competes in the HIPAA-compliant telehealth platform space.

JW Player Key Features

JW Player comes with several capabilities that meet healthcare video requirements:

• HTML5 player compatible across desktops, tablets, and smartphones
• Live streaming with DVR functionality
• Automatic quality adjustments based on bandwidth
• Search within videos for precise navigation
• Customizable player interface with healthcare branding options
• Dashboard for tracking viewer behavior

JW Player Pros

The numbers tell a compelling story. JW Player’s adoption rates show that 88% of customers saw video viewing increase by more than 10% after implementation. Teams reported productivity improvements of over 10% right after setup.

JW Player handles video encoding with impressive speed – adaptive bitrates complete in under 2 minutes. The platform keeps content secure with DRM protection and encrypted streams. Healthcare organizations benefit from RESTful endpoints, JavaScript libraries, and CMS platform integrations.

JW Player Best Use Case

JW Player shines when healthcare providers need quality playback for patient education content. The platform’s precise navigation features make it ideal for medical training videos. Healthcare events stream reliably, and the platform integrates smoothly with telehealth APIs that need dependable video.

Dolby.io (Voxeet)

Dolby.io (formerly Voxeet) brings Hollywood-grade audio technology to HIPAA-compliant telehealth platforms through its communication APIs.

Dolby.io (Voxeet) Key Features

Dolby’s platform gives you powerful telehealth capabilities:

• Spatial audio powered by Dolby Atmos technology creates lifelike conversations
• Advanced noise reduction and echo suppression deliver crystal-clear patient interactions
• HD video connects with ultra-low latency
• Broadcasting and screen-sharing enable virtual medical demonstrations
• Media processing APIs boost dialog levels to increase patient involvement

Dolby.io (Voxeet) Pros

We rolled out the implementation quickly, Physitrack completed their setup in just three months after their first contact. The call quality stays exceptional even under heavy loads and handles nearly 100,000 weekly appointments with almost five million call minutes daily during COVID-19 surges. 

The platform’s pricing structure makes sense, with 30,000 free interactivity minutes and 200 media processing minutes in their trial.

Dolby.io (Voxeet) Best Use Case

Dolby.io works best for distance healthcare that needs superior audio quality. Physical therapy applications see huge benefits, as shown by Physitrack’s successful implementation. Virtual care software providers love its engineering support, which Physitrack’s CEO called “100% unique to Dolby”.

Voximplant

Voximplant provides a cloud communication platform that enables instant voice and video connections in healthcare settings.

Voximplant Key Features

The platform comes with a comprehensive toolkit for medical communication:

• WebRTC technology enables seamless voice and video calls between doctors and patients
• Voice programming features speech recognition and synthesis to enhance accessibility
• JavaScript runs smoothly in a serverless environment that speeds up development
• Patient routing through interactive voice responses streamlines call management
• End-to-end encryption protects sensitive patient information
• Multiple AI integrations support OpenAI, Google Gemini, and ElevenLabs

Voximplant Pros

Voximplant’s reach extends to over 30,000 companies across 190+ countries, handling 150 million calls each month. Their success in telehealth implementation shows through real results – a clinic launched its telemedicine service right before peak pandemic restrictions hit.

The platform’s integration capabilities shine through iOS and Android SDKs, JavaScript for web applications, and REST API that connects backend systems.

Voximplant Best Use Case

Healthcare providers can leverage several powerful scenarios:

• Patient scheduling systems run efficiently with automated voice notifications.
• Virtual waiting rooms help patients stay updated during consultation wait times.
• Secure telehealth connections bridge the gap between doctors and patients.

Final Words:

Each tool in this list solves a slightly different part of virtual care. Some focus on appointment flows and documented visits, with recording, transcripts, and searchable playback. Others prioritize scale, low latency, or combined conferencing and live streaming for education.

Open-source approaches can fit teams that want lightweight control, while enterprise video stacks lean on analytics, content protection, and broad device support. Security features vary, so pay attention to access controls, encryption, and data residency. 

The right choice depends on what you cannot afford to get wrong, missed joins, weak documentation, limited bandwidth, or lack of insight into visit quality over time.

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