Osteofibrous Dysplasia

Campanacci Disease, Cortical Osteofibrous Dysplasia, Ossifying Fibroma

CLINICAL SUMMARY

Osteofibrous dysplasia is a distinctive intracortical lesion almost always seen in the anterior tibial cortex. Histologically, it resembles fibrous dysplasia. Small lesions can be observed, whereas curettage may be needed for larger ones, although it is associated with a high recurrence rate. Extensive bone involvement may lead to deformity and repeated fractures.

DIAGNOSTIC FEATURES

History	Most commonly younger than 10 years of age; rare after 16 years Persistent mild pain Extensive disease can present with multiple fractures or tibial bowing
Location	Intracortical, diaphyseal, elongated Larger lesions can appear to involve the medullary canal Distribution: almost exclusively found in the anterior tibia and/or fibula May be multifocal in the tibia and fibula
Margins	Lytic regions demonstrate geographic margins Some expansile remodeling can be seen, but no soft tissue mass
Matrix	Fibrous or fibro-osseous Remnant cortex may demonstrate marked sclerosis