Inferior Clinical Outcomes and Increased Conversion to Total Hip Arthroplasty Following Hip Arthroscopy for Femoroacetabular Impingement Syndrome in Patients With Inflammatory Joint Disease: A Minimum 5-Year Matched Cohort Study

Purpose

To evaluate midterm clinical outcomes of hip arthroscopy for femoroacetabular impingement syndrome (FAIS) in patients with inflammatory joint diseases (IJD) compared to a matched control group without IJD.

Methods

Data were prospectively collected on all hip arthroscopies performed between February 2008 and December 2018 at a single center. Patients diagnosed with IJD undergoing primary hip arthroscopy for FAIS with labral tears were included. Exclusion criteria were prior ipsilateral hip conditions (except IJD), hip dysplasia (lateral center-edge angle <18°), and Tönnis grade >1. Patients with a minimum 5-year follow-up were matched 1:3 to controls based on age, sex, body mass index, and Tönnis grade. Patient-reported outcomes (PROs), rates of achieving clinically relevant thresholds, and secondary procedures were compared between groups.

Results

A total of 27 hips (23 patients) with IJD were matched to 81 hips (79 patients) in the control group. At a minimum 5-year follow-up, both groups showed significant improvement in all PROs. However, the IJD group had lower postoperative PRO scores and fewer patients meeting patient acceptable symptom state for modified Harris Hip Score and Non-Arthritic Hip Score (29.6% vs 61.7% and 40.7% vs 64.2%). The IJD group had significantly higher odds of requiring a second hip surgery (odds ratio, 3.57; 95% confidence interval, 1.04-12.23; P =.042) and lower odds of maintaining arthroplasty-free survivorship (odds ratio, 0.14; 95% confidence interval, 0.04-0.56; P =.003).

Conclusions

Patients with IJD undergoing hip arthroscopy for FAIS experience significant improvement in PROs at midterm follow-up. However, they achieve clinically significant thresholds less frequently, exhibit increased revision arthroscopy rates, and have higher rates of conversion to total hip arthroplasty compared to the control group.

Level of Evidence

Level III, retrospective comparative case series.

Inflammatory joint diseases (IJDs) such as rheumatoid arthritis and systemic lupus erythematosus are severe, debilitating conditions characterized by systemic inflammation and progressive joint degradation, resulting in pain, disability, diminished quality of life, and a reduced life span. ,, Advancements in medical management, particularly with disease-modifying antirheumatic drugs, have improved outcomes and reduced the need for surgical interventions. , However, despite this progress, patients often still require total hip arthroplasty (THA) due to progressive joint disease. The outcomes and complications of patients with IJD undergoing total hip arthroplasty have been extensively studied, revealing higher perioperative complication rates related to cardiovascular disease, bone loss, poor soft tissue quality, and qualitative or quantitative deficiencies of the immune system. ,,, Additionally, the use of immunosuppressive medication may increase the risk of perioperative infection, whereas the discontinuation of these medications perioperatively, as sometimes advised, may predispose patients to postoperative flare-ups and potentially impact recovery.

Hip arthroscopy has emerged as a viable treatment option for addressing labral pathology and femoroacetabular impingement syndrome (FAIS) in patients with inflammatory joint diseases.

In the general population, treating FAIS with hip arthroscopy has been proven to yield excellent outcomes. ,,,,, Yet, the outcomes of hip arthroscopy among patients with IJD have been minimally explored beyond short-term follow-up. ,, The purpose of this study was to evaluate midterm clinical outcomes of hip arthroscopy for FAIS in patients with IJDs compared to a matched control group without IJDs. We hypothesize that hip arthroscopy in patients with inflammatory joint disease will result in significant improvements in pain and function at a minimum 5-year follow-up, but the magnitude of improvement may be lower compared to the control group due to the systemic nature of IJD and potential disease-related complications.

Methods

All patients included in this study participated in the American Hip Institute Registry. Data on some of these patients (n = 19) were reported in prior studies, but the present study is a unique analysis. All data collection and reviews retrospectively received institutional review board approval. No funding was received for this study.

Patient Selection Criteria

Patient data were prospectively collected from patients who underwent hip arthroscopy from February 2008 to December 2018 ( Fig 1 ). Patients were excluded if they had previous ipsilateral hip conditions besides IJD, a lateral center-edge angle (LCEA) <18°, previous ipsilateral hip surgery, or preoperative Tönnis osteoarthritis grade >1. The inclusion criteria for this study were patients undergoing primary hip arthroscopy with a rheumatologist-confirmed diagnosis of IJD (rheumatoid arthritis, systemic lupus erythematosus) at the time of surgery. Additional inclusion criteria included completion of preoperative and a minimum 5-year follow-up of patient-reported outcomes (PROs). The PROs assessed in this study included the modified Harris Hip Score (mHHS), Non-Arthritic Hip Score (NAHS), Hip Outcome Score–Sports-Specific Subscale (HOS-SSS), and visual analog scale (VAS) for pain. , Patient satisfaction was rated on a 0 to 10 scale, with 0 being completely dissatisfied with their surgical outcomes and 10 being completely satisfied with their surgical outcome. ,, Rates of meeting previously defined patient acceptable symptom state (PASS), substantial clinical benefit (SCB) thresholds, and maximal outcome improvement were compared. ,,,, Minimal clinically important difference (MCID) was calculated via the distribution method using preoperative PROs. Complications were postoperatively documented in clinical visits and follow-up questionnaires.

Fig 1

Patient selection flow diagram.

Surgical Technique

All surgeries were performed under general anesthesia in the supine position on a traction table by the senior author (B.G.D.). For each arthroscopy, a minimum of 2 portals were used (the anterolateral and mid-anterior portals). Other portals were used on a case-by-case basis. Interportal capsulotomy with a blade was used to access the joint. While in the joint, diagnostic arthroscopy was used to initially assess the labrum, intra-articular cartilage, and ligamentum teres. Labral tears were classified using the Seldes classification system. Femoral head chondral pathologies were noted with the acetabular labrum articular disruption and Outerbridge classifications. , Tear of the ligamentum teres were defined using the Domb and Villar classifications. ,

With the use of a burr under fluoroscopic guidance, acetabular osseous deformities and femoral head-neck osseous deformities were corrected. Considering labral pathology, labral tears were selectively debrided or repaired to maximize stability based on arthroscopic findings. If the labral tear was unrepairable, hamstring allografts were used to perform a labral reconstruction. If full-thickness chondral defects were present, microfractures were performed. Patients who had a presurgical history of painful, internal snapping hip syndrome received an iliopsoas fractional lengthening. Iliopsoas fractional lengthening was performed by cutting the iliopsoas tendon at the muscle-tendon junction, leaving the muscular region intact. Ligamentum teres tears were treated with debridement. With a multifactorial consideration of age, range of motion, generalized ligamentous laxity, acetabular coverage, and arthritic changes, the capsule was repaired or plicated.

Matching Design

Using R (version 4.3.2), propensity matching to a cohort of patients without inflammatory joint disease was used to control for potentially confounding variables. IJD hips were matched to control hips in a 1:3 ratio based on age at the time of surgery, sex, preoperative Tönnis grade, and body mass index (BMI) as matching parameters with an optimal pair matching algorithm. Matching was performed until no further matches could be made.

Statistical Analysis

An a priori power analysis was used to determine the sample size needed in each matched group to achieve 80% power with an α of 0.05. A treatment sample size of 17 was determined to achieve 80% power. For continuous variables, the Shapiro-Wilk test was performed to test for normal distribution, with P >.05 indicating normality. The paired 2-tailed t test or Wilcoxon signed-rank test was used to compare continuous data between groups. To detect significant differences between categorical variables, the χ 2 and Fisher exact tests were used. Descriptive statistics, including means, standard deviations, and proportions, were reported when relevant.

Using the distribution method, the MCID for the IJD and control groups was 8.97 and 6.71 for the mHHS, 10.02 and 6.68 for the NAHS, and 12.07 and 9.95 for the HOS-SSS. SCB and PASS values for the mHHS, NAHS, and HOS-SSS were compared to previously defined values from the literature. ,,

Results

Patient Demographic Characteristics

All 27 IJD hips (23 patients) were matched to 81 control hips (79 patients). Table 1 summarizes demographic characteristics of the study groups. Between the IJD group and the control group, there was no significant difference in age at surgery, BMI, and sex ( P >.05). The control group was diagnosed with no IJDs ( P <.01). There were no significant differences in radiographic findings. All patients in each group underwent labral treatment, addressing the cause of FAIS and the presence of ligamentum teres tears ( P <.05) ( Table 2 ).

Table 1

Demographic Characteristics

Characteristic IJD Control P Value
Total matched, n 27 81
Follow-up time, mo 89.54 ± 28.41 82.87 ± 8.75 .87
Age at surgery, y 41.39 ± 13.97 42.37 ± 14.52 .85
Body mass index 25.71 ± 4.59 26.37 ± 5.79 .86
Sex
Male 4 (14.8) 10 (17.5) >.99
IJD diagnosis <.01
Rheumatoid arthritis 25 (92.58) 0 (0) NA
Lupus 2 (7.42) 0 (0) NA
DMARDs prescribed 17 (62.96) 0 (0) NA

NOTE. Values are presented as number (%) or mean ± standard deviation unless otherwise indicated. Bold values indicate statistical significance at P <.05.

DMARD, disease-modifying antirheumatic drug; IJD, inflammatory joint disease; NA, not applicable.

Table 2

Intraoperative Findings

Characteristic IJD, n (%) Control, n (%) P Value
Seldes labral tear type .024
0 0 (0.0) 3 (3.7)
1 8 (29.6) 15 (18.5)
2 9 (33.3) 50 (61.7)
1 & 2 10 (37.0) 13 (16.0)
ALAD grade .16
0 4 (14.8) 5 (6.2)
1 6 (22.2) 27 (33.3)
2 7 (25.9) 30 (37.0)
3 8 (29.6) 18 (22.2)
4 2 (7.4) 1 (1.2)
Acetabular Outerbridge .043
0 3 (11.1) 5 (6.2)
1 7 (25.9) 27 (33.3)
2 7 (25.9) 30 (37.0)
3 5 (18.5) 17 (21.0)
4 5 (18.5) 2 (2.5)
Femoral head Outerbridge .06
0 15 (62.5) 70 (86.4)
1 1 (4.2) 0 (0.0)
2 2 (8.3) 3 (3.7)
3 3 (12.5) 3 (3.7)
4 3 (12.5) 5 (6.2)
LT tear (Domb) .006
0 9 (34.6) 43 (53.1)
1 3 (11.5) 3 (3.7)
2 4 (15.4) 25 (30.9)
3 10 (38.5) 10 (12.3)
LT tear (Villar) .009
0 10 (37.0) 43 (53.1)
1 3 (11.1) 3 (3.7)
2 4 (14.8) 25 (30.9)
3 10 (37.0) 10 (12.3)
Loose bodies 5 (18.5) 7 (8.6)
Notch osteophytes 1 (3.7) 13 (16.0)

ALAD, acetabular labrum articular disruption; LT, ligamentum teres.

Radiographic Findings

Preoperatively, the IJD group had 5 (18.5%) patients with Tönnis grade 1, an average LCEA of 32.91° ± 8.53 ° , an average α angle of 59.15° ± 17.60 ° , and an average Tönnis angle of 5.50° ± 4.96°. The control group had 9 (11.1%) patients with Tönnis grade 1, an average LCEA of 31.69° ± 6.17 ° , an average α angle of 58.69° ± 10.85°, and an average Tönnis angle of 4.30° ± 5.11 °. There were no significant differences between the 2 cohorts for preoperative Tönnis grade ( P =.51), LCEA ( P =.42), α angle ( P =.88), and Tönnis angle ( P =.62).

Postoperatively, the IJD group had 4 (15.4%) patients with Tönnis grade 1, an average LCEA of 30.47° ± 6.59 ° , an average α angle of 44.04° ± 5.63 ° , and an average Tönnis angle of 4.88° ± 3.60°. The control group had 7 (10.4%) patients with Tönnis grade 1, an average LCEA of 30.46° ± 5.91 ° , an average α angle of 43.67° ± 5.16°, and an average Tönnis angle of 4.70° ± 4.30 °. There were no significant differences between the 2 cohorts for preoperative Tönnis grade ( P =.76), LCEA ( P =.99), α angle ( P =.77), and Tönnis angle ( P =.84).

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Jun 27, 2026 | Posted by in PHYSICAL MEDICINE & REHABILITATION | Comments Off on Inferior Clinical Outcomes and Increased Conversion to Total Hip Arthroplasty Following Hip Arthroscopy for Femoroacetabular Impingement Syndrome in Patients With Inflammatory Joint Disease: A Minimum 5-Year Matched Cohort Study

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