General Principles
Physiology of Cold Exposure
Mechanisms of Heat Loss
Radiation
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Radiation involves the direct emission or absorption of heat energy from the body (mostly infrared radiation).
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Radiation is the largest source of heat loss from the body.
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Clothed, sedentary individuals in a calm, temperate climate lose more body heat (approximately 60%) by radiation than active individuals (approximately 45%) in a thermoneutral environment where heat production equals heat loss.
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The human body constantly radiates heat to nearby solid objects with a cooler temperature, and the rate of heat loss increases with the difference in temperature between the body and the object.
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Radiant heat loss increases as temperature decreases but only becomes a significant concern in extremely cold environments.
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Clothing does not markedly affect radiant heat loss.
Evaporation
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Evaporation occurs when water or moisture is transformed into vapor.
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Evaporation occurs with perspiration on the body’s surface and in respiratory passages as inspired air is warmed and moistened.
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High altitude increases heat and water losses from the lungs because breathing deepens and the respiratory rate increases.
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A small amount of “insensible” perspiration occurs at cold temperatures but may become significant in active individuals who are not appropriately dressed for that temperature.
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Vigorous exercise with increased sweating leads to greater evaporative heat loss than with normal evaporative loss in sedentary individuals in a temperate climate (a difference of approximately 20%–30%).
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Vapor barrier systems meant to decrease evaporative water loss are primarily ineffective in physically active individuals because they trap perspiration between the barrier and the skin and lead to increased heat loss by convection when the sweat rate exceeds the rate of permeability ( Fig. 22.1 ).
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Wet clothing combined with wind leads to significant evaporative heat losses.
Convection
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Convection involves the transfer of heat from the body to cold air or water in contact with the body surface.
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Ongoing heat loss occurs when warmed air or water is continually displaced from the body surface and is replaced by air and water of colder temperatures.
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The amount of heat loss that occurs by convection is determined by the temperature difference between the air and the body surface and by the speed of the air moving over the body.
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Convective heat loss increases greatly with wind moving over the body surface, particularly with submersion in cold water.
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In addition to natural wind, wind moving over the body surface created by cycling, skiing, running, windsurfing, or other activities that increase air flow over the body can cause marked heat loss, particularly at cold temperatures sustained over prolonged periods.
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“Wind chill” is wind combined with cold that causes a lower “equivalent” temperature ( Fig. 22.2 ) than current environmental temperature and greatly accelerates heat loss by convection; wind chill is most significant with the first 20 mph increase in wind speed, with some additional effects at higher wind speeds.
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Cold-water swimmers lose significant heat by convection because continuous motion prompts the ongoing displacement of water away from the body, resulting in constant exposure of a “warm” body to cold water.
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Windproof clothing, particularly combined with appropriate insulation layers, can greatly reduce convective heat loss in most environments by trapping warm air and minimizing air displacement.
Conduction
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Conduction involves the direct transfer of heat from the body when it is in contact with a surface colder than the body’s temperature (e.g., water, snow, ice, or rocks).
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Water is an excellent conductor, and it has an exponentially greater volumetric heat capacity than air, which can lead to significant heat losses for anyone immersed in cold water, particularly without protective clothing.
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In addition, wet clothing increases conductive heat losses.
Mechanisms of Heat Production
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Metabolic and biochemical reactions (slight increase)
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Muscular activity
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Involuntary shivering (increases heat production 2–6 times the basal levels; subsides after several hours when core temperature drops below 30°C [86°F])
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Voluntary exercise (increases heat production up to 10 times the basal levels)
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Nonshivering thermogenesis
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Increases thyroxine, epinephrine, and norepinephrine and a subsequent slight increase in overall tissue metabolism
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Relatively ineffective in preventing cold injury; may increase heat production by 10%–15% in adults
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Thermoregulation and Physiologic Adaptations
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The hypothalamus is the thermoregulatory center for maintenance of body temperature and physiologic response to cold.
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The body needs to stay between 34°C and 40.5°C (95°F and 105°F) to maintain normal organ function; core temperature normally ranges between 36.5°C and 37.5°C (97.7°F–99.5°F).
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The body dissipates heat relatively efficiently but is less effective at compensating for cold.
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The body initially responds to cold by regulating the core (brain and other major organs) and shell (skin, muscle, and extremities) .
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Exposure to cold stimulates thermoreceptors in the skin that signal the hypothalamus to activate shivering and nonshivering thermogenesis, constrict peripheral or “shell” circulation, and decrease sweating in an effort to increase heat production and maintain core temperature.
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The body shell acts as an interface between the body and environmental stresses—shell temperature may vary widely in contrast to core temperature.
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Athletic performance may be decreased with shell cooling as cold weakens and slows muscle contractions, decreases tissue elasticity, and slows nerve conduction.
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Prolonged cooling causes body core temperature to drop and results in several physiologic changes:
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When core temperature falls below 35°C (95°F), rates of essential biochemical reactions decelerate.
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Shivering gradually ceases at approximately 31°C–32°C (88°F–90°F) as muscles become cooler and stiffer.
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Severe cold may affect all organ systems, particularly the central nervous system (CNS) and the cardiovascular system ( Table 22.1 ).
TABLE 22.1
System
Mild Hypothermia (35°C–32°C [95°F–90°F])
Moderate Hypothermia (32.2°C–28°C [90°F–82.4°F])
Severe Hypothermia (<28°C [82.4°F])
Central nervous system
Confusion, slurred speech, impaired judgment, amnesia
Lethargy, hallucinations, loss of papillary reflex, EEG abnormalities
Loss of cerebrovascular regulation, decline in EEG activity, coma, loss of ocular reflex
Cardiovascular system
Tachycardia, increased cardiac output, and systemic vascular resistance
Progressive bradycardia (unresponsiveness), decreased cardiac output, BP, atrial and ventricular arrhythmias, J (Osborn) wave on EKG
Decline in BP and cardiac output, ventricular fibrillation (28°C [82.4°F]) and asystole (20°C [68°F])
Respiratory system
Tachypnea, bronchorrhea
Hypoventilation (decreased RR and tidal volume), decreased oxygen consumption and CO 2 production, loss of cough reflex
Pulmonary edema, apnea
Renal
Cold diuresis
Cold diuresis
Decreased renal perfusion and GFR, oliguria
Hematologic
Increase in hematocrit, decreased platelet and white blood cell counts, coagulopathy, and DIC
Gastrointestinal
Ileus, pancreatitis, gastric stress ulcers, hepatic dysfunction
Metabolic/endocrine
Increased metabolic rate, hyperglycemia
Decreased metabolic rate, hyper- or hypoglycemia
Musculoskeletal
Increased shivering
Decreased shivering (32°C [89.6°F])
Patient appears dead “pseudorigor mortis”
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As temperature decreases, heart rate and cardiac output reduce, and arrhythmias may occur secondary to myocardial irritability.
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Cerebral blood flow decreases, leading to dilated pupils, obtundation, stupor, and eventually coma.
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Respiratory rate reduces and so does oxygen consumption.
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Diuresis occurs secondary to shunting of blood volume to the body core from the periphery.
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Lactic acidosis develops secondary to decreased shell tissue perfusion (decreased tissue oxygenation) and subsequent anaerobic glycolysis combined with carbon dioxide retention that occurs with reduced respiratory rate.
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Insulin activity reduces and hyperglycemia develops.
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Exercise in the Cold
Sports Associated With Cold Injury
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Any cold-weather or cold-water sport can be associated with cold injury.
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Risk of cold injury corresponds with level of cold exposure, wind, precipitation, and athlete’s preparation for cold exposure.
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Specific sports may include skiing (all types), snowshoeing, mountaineering and rock climbing, snowmobiling, canoeing, kayaking, white-water rafting, open-water swimming, and skating. Windsurfing and small-boat sailing may result in cold injury after unexpected capsizing. Moreover, unprepared runners, hikers, backpackers, and cyclists may experience significant cold injuries, particularly with prolonged and inadequate exposure combined with unexpected weather (e.g., blizzard, cold rain, high winds, dropping temperature, and wind chill).
Prevention
Almost all cold illness is caused by exposure to cold, often unexpected, without adequate protection. Appropriate planning is imperative to prevent cold illness and injury.
Increase Heat Production
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Increasing heat production is the least effective way to prevent cold illness.
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Exercise: voluntary muscular activity will produce heat
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Shivering: involuntary muscular activity will also produce heat
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Eating: frequent meals or snacks are needed to replenish glycogen and fat stores, particularly with prolonged exercise in cold environments
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Hydration: consume adequate fluids to prevent dehydration and subsequent impairment in circulating blood volume
Decrease Heat Loss
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Decreasing heat loss is the most effective way to prevent cold illness.
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Physiologic mechanisms for increasing heat production are much less effective than strategies applied to decrease heat loss.
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Heat loss is primarily prevented with adequate layering of clothing.
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Insulation and permeability are important properties of cold weather clothing.
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Most versatile cold weather clothing systems are usually composed of three layers:
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Inner hydrophobic polyester fabric (e.g., Capilene, Coolmax, Thermax, Thermolite, or Thermostat) that allows wicking of moisture away from the body. Avoid cotton.
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Middle insulating material can be a second light layer (similar to inner layer fabric) or a heavier layer (can cause overheating; best used during exercise warm-up, cool-down, or in extremely cold environments) such as wool and wool/synthetic blends (heavy when wet but excellent insulator even then), pile and fleece (varying weights offer versatility for exercising athletes, fleece replacing pile), synthetic fillers (e.g., Primaloft, Liteloft, Dacron, Hollofill, Quallofil, or Thinsulate), or down (good in cold dry conditions, loses insulating properties when wet); the middle layer can lead to overheating.
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Outer protective shell that is windproof and water repellant (e.g., newer treated nylons):
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Newer treated nylons are best because they offer highest breathability: fibers are tightly woven, and sprays are used to increase water repellency.
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Laminates such as Gore-Tex and other brand-specific materials designed to mimic Gore-Tex are advertised as “waterproof” and breathable, but the amount of sweat produced during exercise can exceed the capability of the laminate to transmit water vapor.
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To date, an ideal fabric that allows water vapor to pass outward but not inward has not been developed.
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Breathability of the outer layer is inversely proportional to the degree of water repellency and waterproofing; adequate breathability is important during exercise.
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Middle and outer layers should each be slightly larger than the direct inner layer to allow a narrow space for warm air trapping; avoid “tight” layering.
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The primary goal with layering is to stay relatively warm without excessively sweating or overheating, and layers must be shed or added depending on current activity levels and environmental conditions.
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Ventilation ports in certain outer garments may be opened for adequate breathing and are particularly important when using laminates.
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Excessive sweating causes heat loss through increased evaporation and conduction and may affect the insulating property of certain fabrics.
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Wind chill can cause dangerously large amounts of heat loss through convection without windproof garments and appropriate insulation adjusted to activity levels.
Special Protection
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Special protection and other measures to minimize heat loss and injury should be implemented.
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Prevent significant conductive loss by placing a “barrier” between the body and colder objects (e.g., foam or other sleeping pads such as Therma-Rest, wet or dry suits with cold-water exposure, or leather or plastic boots with an inner insulating layer).
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Maintain adequate trunk warmth to minimize vasoconstriction in hands and feet that may result in subsequent cold injury.
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Wear mittens instead of gloves, preferably with a protective and windproof outer shell and an inner insulating layer.
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Prevent radiant heat loss from the head (blood supply to the head is maintained in cold conditions) by wearing an insulating cap or balaclava and by using a hood when needed (high wind or wet weather).
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Protect the exposed skin of face and ears by using a balaclava or neck gaiter pulled up over the face (neck gaiters also decrease heat loss from relatively superficial, large vessels of the neck).
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Prevent genital injury by wearing undershorts with a windproof front panel.
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Protect eyes (corneal freezing) by using ski goggles.
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Avoid excessive wetting at all times, and if immersed in cold water, minimize movement and pull body into a “tight” position (assume the HELP posture— h eat e scape l essening p osture—which is similar to an “upright fetal” position) to decrease exposed surface area unless close to shore or a boat.
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Adequately warm-up before exercising in cold conditions (may warm-up indoors or use insulated protective clothing if outdoors).
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Avoid the use of emollients on the face because these have been shown to increase the incidence of frostbite and other cold injuries.
External Warming Sources
See Treatment discussion in the Accidental Hypothermia section.