Adamantinoma




CLINICAL SUMMARY


Adamantinoma is a low-grade malignancy that is found almost exclusively in the tibia and fibula of young adults. Histologically, it is distinguished from other bone tumors by the presence of clusters of epithelial cells. Treatment is wide resection of the involved bone.




DIAGNOSTIC FEATURES
























History


  • Young adults, with an average age of 35 years




  • Presents with pain and occasionally swelling

Location


  • Diaphyseal to metadiaphyseal, intracortical



  • Medullary involvement and often soft tissue mass



  • Distribution: The most common site is the tibia (80% to 85%) or tibia plus fibula (5%)

Margins


  • Geographic lytic component can have variable margins



  • Can demonstrate expansile remodeling and cortical thickening

Matrix


  • Mixed lytic and sclerotic






IMAGING
























  • AP x-ray ( left ) showing the intracortical location of an adamantinoma with variable margins.



  • Sagittal CT reconstruction showing more clearly the intracortical origin of the tumor and a longitudinal growth pattern ( right ).


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