This issue of ‘Clinical Rheumatology’ is devoted to a group of diseases that are individually different; however, they share several facts in common ( Table 1 ).
Table 1 
Common trunk of miscellaneous diseases. 
| Individually rare | 
| Collectively important | 
| Emerging | 
| Difficult to diagnose | 
| Difficult to treat | 
| Multidisciplinary | 
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